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Susan J. Mandel, MD, MPH

Degree and Institution

MD, Columbia University College of Physicians and Surgeons

Faculty Title

Professor, Medicine (Endocrinology, Diabetes, and Metabolism)

Research Expertise

Thyroid cancer is the most common endocrine cancer and affects 17,000 people a year. As part of the treatment for thyroid cancer, patients receive therapy with radioactive iodine. Prior to this therapy, they undergo whole body scanning with the I-131 isotope to evaluate the extent of their residual disease after surgery. We are evaluating the use of the I-123 isotope for these pre-therapy scans, which has better imaging characteristics and results in a lower radiation dose to the patients. Our data have demonstrated this is a superior agent for scanning. I have established a multidisciplinary Thyroid Nodule Clinic with Endocrinology/medicine, Ultrasound/Radiology, and Cytology/Pathology to evaluate patients with nodular thyroid disease. The proper diagnostic test for euthroid patients with thyroid nodules is fine-needle aspiration biopsy (FNA). The FNAs are performed with ultrasound guidance and we are analyzing the incremental utility of ultrasound-guided FNA in the care of these patients versus FNA by palpation.

Cancer Program
Center for Head and Neck Cancer
» Endrocrinology

Columbia Presbyterian Medical Center, New York

Brigham and Women's Hospital, Harvard Medical School, Boston MA

Board Certifications
Internal Medicine; Endocrinology, Diabetes & Metabolism


Click here to see my publications

Contact Information

Susan J. Mandel
Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104