Research Programs


Tobacco and Environmental Carcinogenesis Program

Program Leader(s): Robert (“Robbie”) Schnoll, PhD and Trevor M. Penning, PhD

The Tobacco and Environmental Carcinogenesis Program brings together researchers who conducti trans-disciplinary studies that address health issues related to tobacco dependence and environmental carcinogens. The program includes the Center of Excellence in Environmental Toxicology (which has research themes in mechanisms of carcinogenesis and gene-environment interactions that determine cancer risk) and the Center for Interdisciplinary Research on Nicotine Addiction (which has research themes in nicotine addiction and smoking cessation). The scientific goals of the TEC, which have been devised to integrate these research themes, are as follows:

  1. To elucidate the mechanisms by which environmental carcinogens cause cancer,
  2. To identify gene and gene-environment interactions that determine individual susceptibility to carcinogens,
  3. To enhance available approaches for preventing and treating nicotine dependence; and
  4. To develop and validate biomarkers of carcinogen exposure and response.

The TEC program is dedicated to understanding the etiology and developing methods to prevent tobacco and environmental-related cancers at the population, community and individual level.