Program Leader(s): Peter O'Dwyer, MD
Founded in 1993, the Clinical Investigations Program is a highly interactive group of investigators whose energies are focused on the development of more effective diagnostic approaches and therapies for adult patients with neoplastic disease using multimodality therapeutic approaches. The principal goal of the Clinical Investigations Program is to develop novel approaches for the prevention, diagnosis, and treatment of cancer, including new diagnostic strategies, and improved medical, surgical and radiotherapeutic techniques. Program members conduct both fundamental and clinical research. There is emphasis on translational research to expedite the clinical application of innovative therapy. The majority of current research is clustered around six major interdisciplinary research areas: Experimental Therapeutics, Breast Cancer, Gastrointestinal Malignancies, Melanoma, Genitourinary Malignancies and Diagnostic Imaging and Surgical Staging. Program members are responsible for the development and conduct of trials in that particular field with an emphasis on innovative treatment approaches. This program serves as the linkage with Research Programs that are more focused on basic, translational or cancer control research, as evidenced by the significant interprogrammatic collaborations with the Breast Cancer, Melanoma, and Stem Cell Biology and Therapeutics Programs.