Penn Researchers Report a Gene-Therapy Success

May 9, 2012

Philadelphia Inquirer

In continuing coverage, the Phildelphia Inquirer covered news of a new Penn study that showed that cells that were genetically modified to fight HIV have persisted for up to 11 years in patients who participated in trials. "We were astonished that we could detect the modified cells for so long. It's a relatively small number of patients, but more than 500 years of patient data," said Bruce Levine, PhD, an associate professor of Pathology and Laboratory Medicine and director of the Clinical Cell and Vaccine Production Facility. "But it's difficult to separate with certainty the effectiveness of this treatment from the antiretrovirals." The results provide further evidence that gene therapy can be used safely and without causing cancers or other side effects. "I think people have been scared of gene therapy for a long time," Levine said. "Now, maybe we are on the way to enlightenment." Read More

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