The Pancreatic Cancer Dream Team, led by Drs. Craig Thompson and Daniel Von Hoff is conducting clinical trials to test new ways of cutting off fuel supply to pancreatic cancer. One set of trials uses a drug to break through the tough coating surrounding the cancer so that a second drug can kill the cancer cells. This drug combination is showing positive preliminary results in actually shrinking tumors. Another effort is aimed at examining a tumor's metabolism to personalize treatment for individual patients so that the side effects are minimized. The team is also developing new ways to get images of pancreatic cancer, so that the tumor's response to treatment can be observed. This will make personalized treatment a reality for pancreatic cancer patients.