Melanoma is a type of cancer that forms from melanocytes. A melanocyte is a normal cell found in the skin that produces melanin. Melanin is a black or dark brown pigment that is seen in the skin, hair, and parts of the eye.
Melanoma is the most serious form of skin cancer. Other more common, but usually less serious, types of skin cancer include basal cell carcinoma and squamous cell carcinoma.
Of the many different types of melanoma, most are seen in the skin (this also includes nail beds, soles of the feet, and scalp), but melanoma can also occur in the eye, or on mucosal surfaces which include the anal canal, rectum, and vagina.
Pigmented Lesions are skin spots that are brown or black. They are usually moles. Pigmented lesions may change in size, color or border shape. They may itch or sting. Such changes could be warning signs that melanoma may be developing.
Careful monitoring of moles and quick action when they change in a suspicious way are among the steps you and your doctor can take to prevent melanoma and its consequences.
Patients with melanoma or pigmented lesions will be cared for by the team from Penn's Melanoma Program and its Pigmented Lesion/Melanoma Practice.
Different treatments are available for those with melanoma. Some treatments are called standard. This means they are the currently used treatments. Some treatments are being tested in clinical trials. A treatment clinical trial is a study meant to help improve current treatments or obtain information on new treatments.
When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. You may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment, while others are available during or after treatment.
Treatment options vary depending on your situation including the stage of the cancer and other factors that may be... read more Treatment
In 2003 her doctors found a cancerous brain tumor, estimating that she had a year and a half to live. Sallie Nangeroni wanted the best neurosurgeon in the region. She came to HUP. Sally was rightfully scared. Her father died of brain cancer when he was just 40 years old, and her husband's brother had just passed away from a brain tumor. At the time she was diagnosed, Sallie just hoped that she would be able to see all three of her sons graduate from high school. Now, 7 years later, she has seen two of them graduate from college, with one now in medical school. Her next goal is to see her youngest son graduate from college next year.
Peter O'Dwyer, MD, professor of Hematology-Oncology and program director of Development Therapeutics in the Abramson Cancer Center, was interviewed on NBC10's 10! Show about Penn's work as part of the Stand Up to Cancer Dream Team... Read more