Stomach Cancer (Gastric)

About Stomach Cancer

At Penn Medicine, patients with stomach cancer receive their care from a multidisciplinary team of nationally recognized experts in the diagnosis, treatment and research of gastrointestinal cancer.

Stomach cancer, also called gastric cancer, is cancer that forms in tissues that line the stomach. The stomach is a hollow organ in the upper abdomen, just under the ribs. Its primary function is to receive food from the esophagus, digest it and turn it to liquid/semi-liquid and send it through the lower digestive tract.

The stomach has five layers:

  • Inner layer: lining of the stomach
  • Submucosa: support tissue for inner layer
  • Muscle layer: muscles of the stomach
  • Subserosa: support tissue for the outer layer
  • Outer layer: outer lining, also called serosa

The most common type of stomach cancer is called adenocarcinoma. Adenocarcinoma is cancer that starts in cells that have gland-like properties within the tissues that line the inside of the stomach.

Other types of stomach cancer include:

  • Lymphoma
  • Leiomyosarcoma
  • Stromal Tumor (GIST)

These types of stomach cancer are relatively uncommon.

Stomach cancer is relatively uncommon in the United States, and its rate of incidence has declined over in the past decades. Experts believe this decline may be due, in part, to the reduced intake of salted, cured and smoked foods.

Penn Medicine’s multidisciplinary approach to cancer diagnosis and treatment provides better outcomes and gives patients access to the most advanced treatment, surgical techniques and clinical trials.

Because navigating a cancer diagnosis and treatment options can be difficult, patients who wish to connect with a cancer specialist at Penn Medicine can speak with a cancer nurse, who can help them make an appointment with the right physician.

To connect with a cancer nurse at Penn Medicine, patients should call 800-789-PENN.

Read more About Stomach Cancer

Diagnosing Stomach Cancer

An accurate cancer diagnosis from trusted cancer specialists is the first and crucial step in getting personalized treatment options to treat stomach cancer.

Patients who choose Penn’s Abramson Cancer Center, benefit from a multidisciplinary team of cancer specialists including gastroenterologists, radiologists, pathologists and surgeons who work together to provide a diagnosis and joined with radiation oncologist and medical oncologists to have an appropriate treatment plan custom designed for each patient with stomach cancer.

Cancer specialists at Penn Medicine are highly experienced in using the most advanced techniques for diagnosing stomach cancer and are actively researching better and more precise ways to detect stomach cancer.

Because an accurate diagnosis is a critical step in planning cancer treatment, it’s important patients know that when they come to Penn Medicine’s Abramson Cancer Center, they are taking an important step in getting the best cancer treatment.

Navigating a cancer diagnosis and treatment options can be difficult, patients who wish to connect with a cancer specialist at Penn Medicine can speak with a cancer nurse, who can help them make an appointment with the right person. Penn Medicine’s contact center has experienced cancer nurses available and ready to guide patients in finding the cancer specialist right for them.

To connect with a cancer nurse at Penn Medicine, patients should call 800-789-PENN.

Read more Diagnosing Stomach Cancer

Stomach Cancer Treatments

Following the diagnosis and staging of stomach cancer, cancer specialists at Penn Medicine’s Abramson Cancer Center develop a personalized treatment plan. Penn’s treatment options for stomach cancer include:

  • Surgery
    • Partial gastrectomy
    • Total gastrectomy
  • Radiation therapy
    • 3-D conformal radiation therapy
    • Intensity-modulated radiation therapy (IMRT)
    • Proton therapy
    • Volumetric-modulated arc therapy (VMAT)
  • Chemotherapy and biologic therapies
    • Biologic (targeted) therapy
    • Chemoradiotherapy
    • Chemotherapy
  • Clinical trials
  • Other treatments
    • Integrative medicine and wellness
    • Palliative care
    • Penn Home Care and Hospice

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Because navigating a cancer diagnosis and treatment options can be difficult, patients who wish to connect with a cancer specialist at Penn Medicine can speak with a cancer nurse, who can help them make an appointment with the right physician.

To connect with a cancer nurse at Penn Medicine, patients should call 800-789-PENN.

Read more Stomach Cancer Treatments

Stomach Cancer Survivorship

Survivorship programs at Penn Medicine are a distinct phase of stomach cancer care and are designed to help patients' transition from their cancer treatment routine to a post-cancer care lifestyle. There are more than 12 million cancer survivors living and thriving today as a result of advances in cancer treatment. However, cancer treatments can result in physical, emotional and financial complications long after the therapy is complete.

Read more Stomach Cancer Survivorship


Todd Sheridan

Todd Sheridan's family members have always supported his love of hockey and were his biggest fan when his team won the Junior A National Championship. They again showed their deep devotion by bringing him to Penn for the best possible cancer care. T

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