About Gastrointestinal Stromal Tumors (GIST)


About Gastrointestinal Stromal Tumors (GIST)

At Penn Medicine, patients with gastrointestinal stromal tumors (GISTs) receive their care from a multidisciplinary team of nationally recognized experts in the diagnosis, treatment and research of gastrointestinal cancer.

Gastrointestinal stromal tumors (GISTs) are a type of soft tissue tumor. GISTs are very rare tumors that start in special cells in the wall of the GI tract, called the interstitial cells of cajal. These cells, often called the "pacemaker cells," regulate body processes like digestion and send signals to the muscles within the gastrointestinal tract to expand and contract, moving food and liquid through the digestive system.

GISTs can occur anywhere within the digestive tract, but are found most frequently in the stomach or small intestine.

Penn Medicine's multidisciplinary approach to cancer diagnosis and treatment provides better outcomes and gives patients with GIST access to the most advanced treatment, surgical techniques and clinical trials.

Because navigating a cancer diagnosis and treatment options can be difficult, patients who wish to connect with a cancer specialist at Penn Medicine can speak with a cancer nurse, who can help them make an appointment with the right physician.

To connect with a cancer nurse at Penn Medicine, patients should call 800-789-PENN.