Esophageal Cancer

About Esophageal Cancer

At Penn Medicine's Abramson Cancer Center, patients with esophageal cancer receive their care from a multidisciplinary team of nationally recognized experts in the diagnosis, treatment and research of gastrointestinal cancer.

Esophageal cancer is cancer that develops within the lining of the esophagus, the muscular tube through which food passes from the mouth to the stomach.

There are two types of esophageal cancer:

  • Squamous cell carcinoma: Cancer that begins in the flat skin-like cells lining the esophagus.
  • Adenocarcinoma: Cancer that begins in the intestinal-type cells that make and release mucus and other fluids.

Penn Medicine's multidisciplinary approach to cancer diagnosis and treatment provides better outcomes and gives patients access to the most advanced treatment, surgical techniques and clinical trials.

Because navigating a cancer diagnosis and treatment options can be difficult, patients who wish to connect with a cancer specialist at Penn Medicine can speak with a cancer nurse, who can help them make an appointment with the right physician.

To connect with a cancer nurse at Penn Medicine, patients should call 800-789-PENN (7366).

Read more About Esophageal Cancer

Diagnosing Esophageal Cancer

An accurate cancer diagnosis from trusted cancer specialists is the first step in developing personalized treatment options for esophageal cancer.

Patients who choose Penn’s Abramson Cancer Center benefit from a multidisciplinary team of cancer specialists including gastroenterologists, radiologists, pathologists and surgeons who work together to provide a diagnosis and treatment plan custom designed for each patient with esophageal cancer.

Cancer specialists at Penn Medicine are highly experienced in using the most advanced techniques for diagnosing esophageal cancer and are actively researching better and more precise ways to detect esophageal cancer.

An accurate diagnosis is a critical step in planning cancer treatment, so it’s important patients know that when they come to the Abramson Cancer Center, they are taking an important step in getting the best cancer treatment available.

Navigating a cancer diagnosis and treatment options can be difficult, patients who wish to connect with a cancer specialist at Penn Medicine can speak with a cancer nurse, who can help them make an appointment with the right physician.

To connect with a cancer nurse at Penn Medicine, patients should call 800-789-PENN (7366).

Read more Diagnosing Esophageal Cancer

Esophageal Cancer Treatment

Following the diagnosis and staging of esophageal cancer, cancer specialists at Penn's Abramson Cancer Center develop a personalized treatment plan. Penn's treatment options for esophageal cancer include:

  • Surgery
    • Esophagectomy
  • Radiation therapy
    • 3-D conformal radiation therapy
    • Intensity-modulated radiation treatment (IMRT)
    • Volumetric-modulated arc therapy (VMAT)
    • Proton therapy
  • Chemotherapy
  • Endoscopy
    • Endoscopic mucosal resection
    • Radiofrequency ablation
    • Integrative medicine and wellness
    • Palliative care
    • Penn Home Care and Hospice

Because navigating a cancer diagnosis and treatment options can be difficult, patients who wish to connect with a cancer specialist at Penn Medicine can speak with a cancer nurse, who can help them make an appointment with the right physician.

To connect with a cancer nurse at Penn Medicine, patients should call 800-789-PENN (7366).

Read more Esophageal Cancer Treatment

Esophageal Cancer Survivorship

Survivorship programs at Penn Medicine are a distinct phase of esophageal cancer care and are designed to help patients' transition from their cancer treatment routine to a post-cancer care lifestyle. There are more than 12 million cancer survivors living and thriving today as a result of advances in cancer treatment. However, cancer treatments can result in physical, emotional and financial complications long after the therapy is complete.

Read more Esophageal Cancer Survivorship


Perry Rothaus

A fifteen-year cancer survivor, Perry Rothaus feels that not enough attention is given to caregivers, and he credits his wife, Judi, with his survival. Judi researched his type of cancer, decided on the Abramson Cancer Center for his care, and and a

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