Breast Cancer

About Breast Cancer

Making the right diagnosis is a critical component of successful cancer treatment. Penn's cancer specialists have wide-ranging experience treating all forms of breast cancer, including those that occur only rarely. Their expert understanding of the disease allows them to create cancer treatment plans that are customized for every patient.

Breast cancer, the uncontrolled growth of cells in the breast, is the most common type of cancer among women, excluding skin cancer. Breast cancer forms in the tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare.

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Breast Cancer Diagnosis

Doctors at Penn Medicine believe that early detection tests for breast cancer save many thousands of lives each year, and that many more lives could be saved if even more women took advantage of these tests.

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Breast Cancer Treatment

Breast Cancer Surgery options include breast-conserving surgery such as lumpectomy and partial mastectomy; total mastectomy; modified radical mastectomy; and radical mastectomy.

Two types of breast reconstructive surgery are offered at Penn: natural tissue reconstruction and breast implant reconstruction.

Radiation therapy options include accelerated partial breast irradiation (APBI), which includes breast brachytherapy and external beam partial breast irradiation; 3-D conformal radiation therapy; image-guided radiation therapy (IGRT); intensity-modulated radiation therapy (IMRT); targeted radiation therapy treatment called MammoSite®; internal mammary node irradiation; and prone breast radiotherapy.

Chemotherapy and biologic therapies for breast cancer include chemotherapy, hormone therapy, immunotherapy, and vaccine therapy.

Breast cancer clinical trials are also available at Penn.

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Breast Cancer Survivorship

There are more than 12 million cancer survivors living and thriving today as a result of advances in cancer treatment. However, cancer treatments can result in physical, emotional and financial complications long after the therapy is complete. Survivorship programs at Penn Medicine are a distinct phase of breast cancer care and are designed to help patients' transition from their cancer treatment routine to a post-cancer care lifestyle.

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Clinical Trials

Breast Cancer Trials

Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery... more